Twaine \t-waine, twa(i)-ne\ as a boy's name is a variant of Twain (Middle English), and the meaning of Twaine is "divided in two".

The baby name Twaine sounds like Dwaine and Thaine. Other similar baby names are Swaine, Twan, Daine, Dwayne, Dwain, Duwaine, Dwane, Gwayne, Gawaine, Owain, Swain, Swayne and Twayn.