Gwayne \g-wayne, gwa(y)-ne\ as a boy's name is pronounced gwayn. It is of Welsh origin, and the meaning of Gwayne is "white hawk". Variant of the medieval name Gawain.
For more information, see also the related name Gavin.
Baby names that sound like Gwayne are Gayne, Gwayn and Gawayne. Other similar baby names are Dwayne and Swayne.