Niobe \ni(o)-be\ as a girl's name is of Greek origin, and the meaning of Niobe is "fern". Mythology: Niobe was a boastful queen of Thebes whose children were killed by Apollo and Diana as a reprimand for her arrogance. She wept continously, and in time she turned into a stone from which water constantly streamed. Anyone with inconsolable sorrow is said to "weep the tears of Niobe".
Baby names that sound like Niobe are Nibia and Nubia. Other similar baby names are Nore, Nioma, Nike, Noe and Tobe.