Lissandra \l(i)-ssand-ra, liss(an)-dra\ as a girl's name is a variant of Alexandra (Greek), Lisandra and Lysandra, and the meaning of Lissandra is "man's defender". See also Lissa.

The baby name Lissandra sounds like Lissandre and Lyssandra. Other similar baby names are Cassandra, Kassandra, Jessandra, Lasandra, Lizandra and Lissandrina.