Josephene \j(o)-sephe-ne, jos(e)-phene\ as a girl's name is a variant of Josephine (Hebrew), and the meaning of Josephene is "Jehovah increases".

The baby name Josephene sounds like Josephyne, Josephyna, Josephina and Josefene. Other similar baby names are Josephe, Joselyne, Joseline, Josepha, Josefine and Josefena.