Gwynne \gw(yn)-ne\ as a girl's name is a variant of Guinevere (Welsh), Gwendolyn (Welsh), Gwyneth (Welsh) and Gwyn (Welsh), and the meaning of Gwynne is "fair one; white and smooth, soft; fair bow; blessed ring; happiness; fair, white, blessed, holy".

The baby name Gwynne sounds like Gwynna, Gwynn and Gwinne. Other similar baby names are Glynn, Glenne, Glynae, Gwenny, Gwennie, Gwenn, Gwynda, Wynne, Gwenni, Gwenna, Gwynneth, Gwinna, Gwinn and Lynne.