Arethusa \a-rethu-sa, ar(e)-thusa\ as a girl's name is of Greek origin. Greek mythology: Arethusa was a nymph pursued by a river god, who was changed by Artemis into a stream to avoid a fate worse than death.
For more information, see also the related name Aretha.
Baby names that sound like Arethusa are Artis, Ardis, Ardyss, Ardys, Ardiss and Artice. Other similar baby names are Artha and Artheia.