Wye \wye-ye\ as a boy's name is a variant of Wyatt (Old English) and Wylie (Old English), and the meaning of Wye is "war strength; clever, crafty".
The baby name Wye sounds like Faye, Fee, Jaye, Jae, Joe and Way. Other similar baby names are Nye, Wyn, Kye, Rye and Tye.