Wilkes \wi(l)-kes\ as a boy's name is of Old English origin. Probably a short form of Wilkins. Presidential assassion John Wilkes Booth.
Wilkes has 3 variant forms: Wilkie, Willkes and Willkie.
For more information, see also the related name William.
Baby names that sound like Wilkes are Alex, Elex, Allex, Aleks, Algis and Feliks.