Niles \n(i)-les\ as a boy's name is pronounced nyles. It is of English origin. Variant of Niall (Irish, Gaelic) "champion". Also possibly "cloud" or "passionate". May also be used in reference to Nilus (Greek), a saint's name, or be derived from the river in Africa. Familiar in modern times due to the character of Dr. Niles Crane in the TV sitcom "Frasier".
Niles has 2 variant forms: Nile and Nyles.
For more information, see also related names Neil and Nelson.