Houston \ho(us)-ton\ as a boy's name is pronounced HEW-ston. It is of Irish, Gaelic and Old English origin, and the meaning of Houston is "Hugh's town; settlement on the hill". Place name. The name's association with the American West is due to the Texan general Sam Houston and the city of Texas that bears his name.
Houston has 4 variant forms: Hewson, Huston, Hutcheson and Hutchinson.
Baby names that sound like Houston are Hasting and Hastings.