Enzio \e-nzio, en-zio\ as a boy's name is a variant of Enzo (Italian, Old German) and Henry (Old German), and the meaning of Enzio is "home ruler".

The baby name Enzio sounds like Ennis, Enneis, Eneas, Anisio, Anso, Ennes, Enos, Inacio, Ignazio and Innis. Other similar baby names are Ezio, Enno, Nunzio and Sanzio.