Brien \b-rien\ as a boy's name is a variant of Brian (Celtic, Irish, Gaelic), and the meaning of Brien is "high, noble".

The baby name Brien sounds like Bren, Bryen and Brion. Other similar baby names are Arien, Erin, Arin, Aren, Arion, Arian, Arren, Bain, Barden, Borden, Barren, Barten, Ben, Bergen, Beven, Boden, Bowen, Braden, Braiden, Brann, Bran, Brae, Breed, Brenn, Brent, Britt, Briton, Brit, Bret, O'Brien, Bryon, Brye, Bryan, Briant, Briano, Bri, Brain, Brice, Brick, Brik, Brigg, Broden, Bron, Brown, Bruin, Bryn, Brysen, Brycen, Byren, Biren, Darien, Dorien, Freen, Rien, Orren, Orin, Oren and Orion.